The couple, who met on the set of Black Swan, wed on Saturday on the California coast of Big Sur, Gossip Cop confirms.
They exchanged vows after dark in a Jewish ceremony attended by family and friends, including Ivanka Trump.
Portman and Millepied, a dancer and choreographer, announced they were engaged and expecting in December 2010.
The pair welcomed son Aleph the following June.
Earlier this year, Portman and Millepied sparked speculation that they had already tied the knot when they stepped out wearing what appeared to be wedding rings.
Now it’s official.